Virginia A. Caine, M.D. is the Director and Chief Medical Officer of the Marion County Public Health Department. She is an Associate Professor of Medicine at Indiana University School of Medicine Infectious Diseases Division. In 2020, the Indianapolis Business Journal (IBJ) named her as one of the 40 Influential People of the past 40 years, as they celebrated 40 Years of Progress in Indianapolis.

She helped set up the first HIV/AIDS healthcare delivery system in Indianapolis, in all the major city hospitals, ten community health centers, and the resource for community-based HIV/AIDS prevention programs.  Her HIV/AIDS program in the past was recognized number one in the country by the White House.

She is Chair of the National Medical Association Infectious Diseases Section, Co-Chair of the NMA HIV/AIDS Section, and member of the National Medical Association COVID-19 Task Force.